Freeze-Drying Flask for Lyophilisation, Wide Mouth with Small Base and Screw Cap, BORO 3.3 Glass

Description

The Freeze-Drying Flask for Lyophilisation, Wide Mouth with Small Base, BORO 3.3 Glass, also known as a lyophilisation flask, laboratory freeze-dry flask or VirTis-compatible vacuum drying flask, is designed for preparing and drying frozen laboratory samples using compatible manifold-type freeze dryers. Manufactured by REACWARE, this flask features heavy-wall borosilicate 3.3 glass, selected for its thermal properties and chemical resistance. Its construction supports laboratory applications involving low-temperature sample preparation and controlled vacuum conditions. The wide-mouth opening allows convenient sample loading, frozen material handling and dried-product recovery. It also provides easier access to the interior during cleaning and preparation between experiments.

A small, flat-bottom design allows the vessel to stand upright on an appropriate laboratory surface. This supports sample handling before freezing and helps reduce unwanted movement during preparation.  During lyophilisation, samples are frozen before being exposed to controlled vacuum conditions. Ice is removed primarily through sublimation, where frozen water changes directly into vapour without passing through the liquid phase. The wide-mouth design also supports shell-freezing procedures, where liquid samples are distributed along the interior glass surface before freezing. This increases the exposed frozen surface area available for subsequent drying.

Each assembly includes one glass vessel, one silicone lid and one glass connecting tube. These components provide the basic arrangement for use with compatible freeze-drying equipment. The flask is designed to accommodate 47 mm diameter filter membranes, provided that the appropriate filter support and sealing components are used. Filter membranes are not confirmed as included. The assembly is intended for selected VirTis-style freeze-drying systems with 3/4-inch Quickseal-type manifold connections. An appropriate glass or stainless steel adapter may be required, depending on the installed manifold valve. Potential equipment includes compatible VirTis BenchTop Pro, Freezemobile, AdVantage and legacy BenchTop systems. Compatibility depends on the specific freeze dryer configuration rather than the equipment brand alone.

Some EYELA and Labconco freeze dryers may also accept compatible flask assemblies through appropriate adapters. Connection diameter, lid configuration and manifold geometry must be checked before ordering. The BORO 3.3 glass has an annealing point of approximately 560°C, a softening point of approximately 820°C and a linear thermal expansion coefficient of 32 × 10⁻⁷/°C. These properties do not represent the safe operating temperature of the complete assembly. The range is suitable for pharmaceutical development, biotechnology, biological sample processing, food science and university research where laboratory freeze-drying equipment is available.

Safety Precautions: Inspect the glass, silicone lid and connecting components before use. Never apply vacuum to cracked or damaged glassware. Avoid sudden temperature changes and verify the complete assembly’s vacuum, temperature and chemical compatibility limits. Each selected product is supplied as one REACWARE freeze-drying flask assembly containing a glass vessel, silicone lid and glass tube. A threaded screw cap, additional manifold adapter, filter membrane and replacement O-rings are not confirmed as included.

LabChoice Australia supplies freeze-drying flasks, lyophilisation glassware and laboratory vacuum accessories for universities, pharmaceutical laboratories, biotechnology facilities and research institutions across Australia.

Specification

• Product: Freeze-Drying Flask for Lyophilisation
• Alternative Names: Lyophilisation Flask / Wide-Mouth Freeze-Dry Flask / VirTis-Compatible Vacuum Flask
• Manufacturer: REACWARE
• Product Type: Laboratory Freeze-Drying Glassware
• Flask Construction: Wide Mouth with Small, Flat Base
• Glass Material: Heavy-Wall Borosilicate 3.3
• Glass Grade: G3.3 / BORO 3.3
• Available Capacities: 75, 125, 300, 600, 900, 1200 and 2000 mL
• Number of Variations: 7
• Wall Construction: Heavy Wall
• Glass Wall Thickness: Not Specified
• Flask Mouth Design: Wide Mouth
• Flask Base Design: Small, Flat Bottom
• Glass Vessel: Included
• Silicone Lid: Included
• Glass Connecting Tube: Included
• Total Confirmed Assembly Components: 3
• Screw Cap: Not Confirmed
• Screw Thread Size: Not Specified
• Filter Membrane Compatibility: 47 mm Diameter
• Filter Membrane Included: Not Confirmed
• Filter Support Configuration: Requires Confirmation
• Intended Connection Type: VirTis-Style 3/4-Inch Quickseal
• Original Labconco Valve Port Options: 1/2 Inch or 3/4 Inch with Appropriate Adapter
• Additional Adapter Materials: Borosilicate Glass or Stainless Steel
• Separate Manifold Adapter Included: Not Confirmed
• Replacement Silicone Seals: Available as Separate Components, Subject to Compatibility
• O-Ring Included: Not Confirmed
• Glass Annealing Point: Approximately 560°C
• Glass Softening Point: Approximately 820°C
• Linear Thermal Expansion Coefficient: 32 × 10⁻⁷/°C
• Maximum Operating Temperature of Complete Assembly: Not Verified
• Silicone Lid Maximum Operating Temperature: Not Verified
• Maximum Operating Vacuum: Not Specified
• Autoclavability of Complete Assembly: Not Confirmed
• Glass Colour: Not Specified
• Primary Function: Laboratory Freeze-Drying and Vacuum Sample Preparation
• Applications: Lyophilisation, Shell Freezing and Laboratory Vacuum Drying
• Suitable Use: Pharmaceutical, Biotechnology, Food Science, Research and University Laboratories
• Supplied As: One REACWARE Freeze-Drying Flask Assembly in Selected Capacity, Including Glass Vessel, Silicone Lid and Glass Connecting Tube