9
Sep
PCR Machines in Australian Labs: Choosing the Right Thermal Cycler for Reliable DNA Amplification
Polymerase Chain Reaction (PCR) is the cornerstone of molecular biology, enabling scientists to amplify DNA with precision. For Australian laboratories, selecting the right PCR machine (thermal cycler) is critical for reliable results, whether in research, diagnostics, or education. At LabChoice Australia, we provide robust PCR solutions tailored for local scientific needs, combining international compliance with practical usability.
Why PCR Machines Matter in Modern Labs
PCR thermal cyclers automate the heating and cooling cycles that replicate DNA. Accuracy in temperature control directly influences amplification efficiency, making machine quality essential. In Australia, labs demand machines that comply with ISO 13485 for medical devices and ASTM E2108 for optical performance to guarantee accuracy and repeatability.
With applications spanning genetics, clinical diagnostics, infectious disease testing, food safety, and forensic science, PCR machines form the foundation of modern molecular workflows.
PCR vs qPCR: Which One Do You Need?
| Feature | Standard PCR (Endpoint) | Real-time PCR (qPCR) |
|---|---|---|
| Output | Presence/absence of DNA | Quantitative measurement (Ct values) |
| Sensitivity | High | Very high (real-time tracking) |
| Cost | Lower | Higher investment |
| Applications | Cloning, sequencing prep | Diagnostics, gene expression |
For teaching labs or routine workflows, a standard PCR machine is often sufficient. For diagnostics, advanced research, and molecular quantification, a qPCR thermal cycler is recommended.
Key Features to Consider When Buying a PCR Machine
- Thermal block design – Ensure uniform temperature distribution for consistent amplification.
- Gradient capability – Allows optimisation of annealing temperatures across samples.
- Capacity – From 16-well portable models to 96-well plates for high-throughput labs.
- Software integration – Modern PCR machines provide intuitive interfaces and data connectivity.
- Service & compliance – Local support, calibration, and ISO-aligned certification ensure trust.
FAQs
Q1: What is the average lifespan of a PCR machine?
With regular servicing, high-quality PCR machines last 5–7 years in routine lab use.
Q2: Can PCR machines be used for COVID-19 testing in Australia?
Yes, qPCR machines are widely used for SARS-CoV-2 diagnostics under TGA and ISO guidelines.
Q3: What’s the difference between PCR and qPCR?
PCR detects the presence of DNA, while qPCR measures DNA in real time, providing quantitative results.
Q4: Do LabChoice PCR machines meet international standards?
All LabChoice PCR machines comply with ISO 13485 and ASTM performance requirements.
Refined References
- ISO 13485: Medical Devices – Quality Management Systems. ISO
- ASTM E2108: Optical Performance of PCR Instruments. ASTM International
- Australian Department of Health: PCR and Diagnostic Testing Guidelines. Health.gov.au
- National Center for Biotechnology Information (NCBI) – PCR Techniques. NCBI
